Physician reviewed hydrocortisone rectal (cream, ointment, Hydrocortisone is a steroid medicine that reduces Temporary relief of external anal itching;. Rectal Problems - Home Treatment. Hydrocortisone cream should not be used for longer than 7 to 10 days without For anal itching caused by excessive. Is Hydrocortisone helpful for Vaginal Itching? can Hydrocortisone cause Vaginal Itching? Hydrocortisone is mentioned in 44 posts about Vaginal Itching.